בָּנָ֥ה עָלַ֛י וַיַּקַּ֖ף רֹ֥אשׁ וּתְלָאָֽה׃
Er hat gegen mich gebaut und mich mit Galle und Mühe umzingelt.
Rashi on Lamentations
Gall and bitter plants. As in, “gall and bitter fruit.”4Devarim 29:17. The Midrash Aggadah [states] that רֹאשׁ, refers to Nevuchadnetzar in the exile of Yehoyachin; and תְלָאָה [refers to] Nevuzaradan, who completed the blow in the days of Tzidkiyahu, and he wearied me.5According to this Midrash, תלאה is an expression similar to Shemos 18:8, where it means travail, hardship. (Sifsei Chachomim)